Ex vivo human skin tissue models for in vitro cosmetic safety and efficacy testing

Ex vivo human skin tissue models play a pivotal role in OECD-compliant cosmetic efficacy and toxicity testing, providing a reliable alternative to traditional animal testing. Two widely used models are the Ex vivo Human Skin Disc Model and the Ex vivo Human Skin Sheet Model. These models enable researchers to assess the efficacy and the safety/potential toxicity of cosmetic products with greater precision, aligning with modern regulatory standards and ethical considerations.
Ex vivo frozen abdominal skin tissue models include :
1 - Human dermatomed abdominal skin discs (~~O~~18 & 20mm)
- for OECD guideline compliant, thickness 200-400µm
- for standard application, thickness > 400µm
2 - Human dermatomed abdominal skin sheets
- for OECD guideline compliant, thickness 200-400µm
- for standard application, thickness > 400µm